The Office of Information Security (ISO) is headed by the Chief Information Security Officer (CISO), who is assisted by two IT Security Analysts. The CISO is responsible for creating and enforcing information security policies, as well as monitoring University-wide security compliance. Some security services may send emails from the CISO's mailbox, ociso@tntech.edu (OCISO).

The current Chief Information Security Officer is Deb Zsigalov.

The CISO is assisted by Senior IT Security Analyst Shawn Albro.

The CISO is also assisted by IT Security Analyst Joseph Cross.